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Old 01-18-2022, 04:33 PM   #6
Pete F.
Canceled
 
Join Date: Jun 2003
Location: vt
Posts: 13,069
Quote:
Originally Posted by The Dad Fisherman View Post
The vaccine doesn't stop you from getting infected with COVID, it doesn't stop you from getting sick with COVID, and it doesn't stop people from spreading COVID.

What it does do is give your body what it needs to fight the virus. You do not get as sick, or for as long, from the virus as someone unvaccinated. By shortening the length of the infection/illness you do cut down on how long you can spread the virus.

No, it's not the fault of the unvaccinated that we are still in a pandemic, that would fall on Mother Nature. It needs to run its course.

Unfortunately, some people need a boogeyman to point the finger at
Posted from my iPhone/Mobile device
Whether vaccination of individual persons for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects members of their households is unclear. We investigated the effect of vaccination of health care workers in Scotland (who were among the earliest groups to be vaccinated worldwide) on the risk of coronavirus disease 2019 (Covid-19) among members of their households.

We evaluated data from 194,362 household members (which represented 92,470 households of 2 to 14 persons per household) of 144,525 health care workers who had been employed during the period from March 2020 through November 2020. The mean ages of the household members and the health care workers were 31 and 44 years, respectively; a majority (>96%) were White. A total of 113,253 health care workers (78.4%) had received at least one dose of either the BNT162b2 (Pfizer–BioNTech) mRNA vaccine or the ChAdOx1 nCoV-19 (Oxford–AstraZeneca) vaccine, and 36,227 (25.1%) had received a second dose.

The primary outcome was any confirmed case of Covid-19 that occurred between December 8, 2020, and March 3, 2021. We also report results for Covid-19–associated hospitalization. The primary time periods we compared were the unvaccinated period before the first dose and the period beginning 14 days after the health care worker received the first dose. No adjustment was made for multiplicity. Events that occurred after any household member was vaccinated were censored. Detailed methods and results, strengths and limitations, and the protocol are provided in the Supplementary Appendix, which is available with the full text of this letter at NEJM.org. This study was approved by the Public Benefit and Privacy Panel (2021-0013), and the scientific officer of the West of Scotland Research Ethics Committee provided written confirmation that formal ethics review was not required.

Cases of Covid-19 were less common among household members of vaccinated health care workers during the period beginning 14 days after the first dose than during the unvaccinated period before the first dose (event rate per 100 person-years, 9.40 before the first dose and 5.93 beginning 14 days after the first dose). After the health care worker’s second dose, the rate in household members was lower still (2.98 cases per 100 person-years). These differences persisted after fitting extended Cox models that were adjusted for calendar time, geographic region, age, sex, occupational and socioeconomic factors, and underlying conditions. Relative to the period before each health care worker was vaccinated, the hazard ratio for a household member to become infected was 0.70 (95% confidence interval [CI], 0.63 to 0.78) for the period beginning 14 days after the first dose and 0.46 (95% CI, 0.30 to 0.70) for the period beginning 14 days after the second dose (Table 1 and the Supplementary Appendix).
Not all the cases of Covid-19 in the household members were transmitted from the health care worker; therefore, the effect of vaccination may be larger.1 For example, if half the cases in the household members were transmitted from the health care worker, a 60% decrease in cases transmitted from health care workers would need to occur to elicit the association we observed (see the Supplementary Appendix). Vaccination was associated with a reduction in both the number of cases and the number of Covid-19–related hospitalizations in health care workers between the unvaccinated period and the period beginning 14 days after the first dose.

Given that vaccination reduces asymptomatic infection with SARS-CoV-2,2,3 it is plausible that vaccination reduces transmission; however, data from clinical trials and observational studies are lacking.4,5 We provide empirical evidence suggesting that vaccination may reduce transmission by showing that vaccination of health care workers is associated with a decrease in documented cases of Covid-19 among members of their households. This finding is reassuring for health care workers and their families.

Anoop S.V. Shah, M.D.
London School of Hygiene and Tropical Medicine, London, United Kingdom

Ciara Gribben, M.Sc.
Jennifer Bishop, M.Sc.
Public Health Scotland, Edinburgh, United Kingdom

Peter Hanlon, M.D.
University of Glasgow, Glasgow, United Kingdom

David Caldwell, M.Sc.
Public Health Scotland, Edinburgh, United Kingdom

Rachael Wood, Ph.D.
University of Edinburgh, Edinburgh, United Kingdom

Martin Reid, B.Sc.
Jim McMenamin, M.D.
David Goldberg, M.D.
Diane Stockton, M.Sc.
Public Health Scotland, Edinburgh, United Kingdom

Sharon Hutchinson, Ph.D.

Frasier: Niles, I’ve just had the most marvelous idea for a website! People will post their opinions, cheeky bon mots, and insights, and others will reply in kind!

Niles: You have met “people”, haven’t you?

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